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Quinine toxicity

Quinine toxicity

Quinine causes cinchonism (nausea, vomiting and tinnitus) in overdose but also blindness which is delayed and sometimes not noticed until the morning after the acute toxicity has resolved. Think of it as aspirin (the salicylism) that causes blindness.

litfl.comAug 23, 2019

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SOLVED: Quinine occurs naturally in the bark of the cinchona tree. For centuries, it was the only treatment for malaria. Quinine contains two weakly basic nitrogen atoms, with Kb1 = 3.3Ã—10^-6 and Kb2 = 1.4Ã—10^-9 at 25Â°C. Calculate the pH of a 0.0176 M solution of quinine in water.

SOLVED: Quinine occurs naturally in the bark of the cinchona tree. For centuries, it was the only treatment for malaria. Quinine contains two weakly basic nitrogen atoms, with Kb1 = 3.3Ã—10^-6 and Kb2 = 1.4Ã—10^-9 at 25Â°C. Calculate the pH of a 0.0176 M solution of quinine in water.

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