Thalidomide scandal - Wikipedia
In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as phocomelia, as well as thousands ...
The Woman Who Stood Between America and a Generation of 'Thalidomide …
2017年5月8日 · Today we know that the drug can cause a range of severe congenital deformities and even infant death when taken by pregnant women for nausea. But at the time, thalidomide’s darker effects were...
Thalidomide: the tragedy of birth defects and the effective ... - PubMed
Thalidomide was a widely used drug in the late 1950s and early 1960s for the treatment of nausea in pregnant women. It became apparent in the 1960s that thalidomide treatment resulted in severe birth defects in thousands of children.
US Regulatory Response to Thalidomide (1950-2000)
2014年4月1日 · Thalidomide, a drug capable of causing fetal abnormalities (teratogen), has caused greater than ten thousand birth defects worldwide since its introduction to the market as a pharmaceutical agent.
Thalidomide‐induced teratogenesis: History and mechanisms
Nearly 60 years ago thalidomide was prescribed to treat morning sickness in pregnant women. What followed was the biggest man‐made medical disaster ever, where over 10,000 children were born with a range of severe and debilitating malformations.
Thalidomide - Wikipedia
Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., ... Prescriptions of thalidomide are accompanied by strict measures to avoid any possibility of use during pregnancy, and thalidomide should be avoided in women wanting to conceive. [21]
The Rise, Fall and Subsequent Triumph of Thalidomide: Lessons …
Originally marketed as a sedative, thalidomide gained immense popularity worldwide among pregnant women because of its effective anti-emetic properties in morning sickness. Mounting evidence of human teratogenicity marked a dramatic fall from grace and led to widespread social, legal and economic ramifications.
The Thalidomide Tragedy and its Lasting Effects - SQ Online
2019年7月10日 · Thalidomide was first marketed in Germany during the mid-1950s as a drug to aid with sleeping problems and insomnia. The drug’s safety was emphasized heavily, and it was advertised as being acceptable for anyone to ingest, including pregnant women and children.
True Story of Thalidomide in the US - USA Thalidomide Survivors
US thalidomide babies, now adults, have never been truly counted, recognized or compensated for their enormous losses. With an estimated 40% infant death rate and an unknown number of miscarriages, the damage caused by the reckless distribution of thalidomide samples to pregnant women in the United States is staggering.
Thalidomide: the untold American story in “Wonder Drug”
2023年7月17日 · The wonder of thalidomide, created by West German drugmaker Gruenthal, was its initial claims to be an effective sedative without side effects. But the drug had undergone only minimal testing, and when it was given to pregnant women to counter morning sickness, many of them lost their babies or gave birth to severely deformed infants.
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