T wave alternans - Wikipedia
Microvolt T wave alternans is defined as an alternation in the morphology of the T wave in an every other beat or AB-AB pattern. It has long been associated with ventricular arrhythmias and sudden death. First recognized nearly a century ago, visually discernible alternans were linked to the rapid onset of ventricular tachyarrhythmias.
Electrophysiological Mechanisms Underlying T-Wave Alternans …
2021年3月4日 · T-wave alternans (TWA) reflects every-other-beat alterations in the morphology of the electrocardiogram ST segment or T wave in the setting of a constant heart rate, hence, in the absence of heart rate variability.
T-wave alternans and arrhythmogenesis in cardiac diseases
2010年11月28日 · T-wave alternans (TWA), a precursor of lethal cardiac arrhythmias and sudden death (Rosenbaum et al., 1994; Armoundas et al., 2002; Narayan, 2006; Verrier and Nieminen, 2010b), has been associated with many cardiac diseases, such as heart failure (Luomanmaki et al., 1975), long QT syndromes (Zareba et al., 1994; Shimizu and Antzelevitch, 1999 ...
T wave alternans: an electrocardiographic sign of cardiac ... - Heart
A 46 year old African American woman with a history of hypertension and seizure disorder was hospitalised for seizures and aspiration pneumonia. On the second hospital day she suddenly became aphasic with loss of power in her left upper and lower extremities. Her ECG revealed sinus rhythm, prolongation of the QT …. View Full Text.
Explaining the clinical manifestations of T wave alternans in …
Non-invasive measurement of beat-to-beat alternation of the electrocardiographic T-wave, referred to as T-wave alternans (TWA), is an important marker of risk for sudden cardiac death (SCD). Is this relationship a mere association or is TWA mechanistically linked to SCD?
Pathophysiological basis and clinical application of T-wave alternans
T-wave alternans testing has shown promise as a noninvasive predictor of potentially lethal ventricular arrhythmias in initial studies of diverse patient populations with structural heart disease. The ultimate role of TWA testing in the armamentarium of noninvasive predictors of mortality awaits further large-scale prospective testing.
Microvolt T-Wave Alternans: Physiological Basis, Methods of …
It discusses the electrocardiographic phenomenon of T-wave alternans (TWA) (i.e., a beat-to-beat alternation in the morphology and amplitude of the ST- segment or T-wave). This statement focuses on its physiological basis and measurement technologies and its clinical utility in stratifying risk for life-threatening ventricular arrhythmias.
Understanding Cardiac Alternans | Circulation Research
2004年3月19日 · Electrical alternans can be observed at the ECG level as alternation of the ST-segment and T-wave amplitude and form; T-wave alternans is commonly referred to as TWA. Clinical Relevance of T-Wave Alternans and Link to Cellular Studies
Cardiac alternans: mechanisms and pathophysiological significance
1999年6月1日 · Recent clinical studies have shown that T-wave alternans in the microvolt range serves an independent predictor of both inducible ventricular arrhythmias and sudden cardiac death . The amplitude of the T-wave alternans is such that it can only be detected using spectral signal-processing techniques.
T-wave alternans: lessons learned from a biophysical ECG model
2012年11月1日 · T-wave alternans (TWA) is an alteration of the ECG T-wave which repeats every other beat. An alternating pattern has been also observed at myocytes level, involving both action potential duration and morphology (mainly in phases 2 and 3).
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