Physostigmine - Wikipedia
Physostigmine (also known as eserine from éséré, the West African name for the Calabar bean) is a highly toxic parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. It occurs naturally in the Calabar bean and the fruit of the Manchineel tree.
Physostigmine Uses, Side Effects & Warnings - Drugs.com
2023年8月16日 · Physostigmine is used to reverse the effects of certain drugs or substances that interfere with this nerve-muscle communication. Such substances include atropine, scopolamine, belladonna, antihistamines, some antidepressants, and other anticholinergic (AN tye KOE lin …
毒扁豆碱 - 百度百科
毒扁豆碱（Physostigmine），化学名称1,2,3,3a-六氢-1,3a,8-三甲基吡咯并 [2,3-b]吲哚-5-酚甲基氨基甲酸酯，是一种有机化合物，化学式为C15H21N3O2，呈白色结晶性粉末，微溶于水，易溶于乙醇，极易溶于氯仿和二氯甲烷，溶于不挥发性油和苯。.
Physostigmine: Uses, Interactions, Mechanism of Action
2005年6月13日 · Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma.
(physostigmine) dosing, indications, interactions, adverse effects, …
ADULT. Dosage Forms & Strengths. injectable solution. 1mg/mL. Anticholinergic Toxicity. Initial: 0.5-2 mg slow IVP (not to exceed 1 mg/min); keep atropine nearby for immediate use. If no response,...
Physostigmine - an overview | ScienceDirect Topics
Physostigmine is a reversible cholinesterase inhibitor that helps prolong the activity of acetylcholine in the body. It is known for its use in treating glaucoma and for stimulating both nicotinic and muscarinic receptors, leading to pupil contraction and ciliary muscle fiber stimulation.
Physostigmine - SpringerLink
2016年10月12日 · Physostigmine salicylate (Antilirium®) is a short-acting, lipid-soluble, nonselective, carbamate cholinesterase (ChE) inhibitor used to increase acetylcholine (ACh) concentrations at cholinergic receptors and most commonly employed in the treatment of anticholinergic-induced delirium.
Physostigmine: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月10日 · Physostigmine is a carbamate which inhibits the enzyme acetylcholinesterase and prolongs the central and peripheral effects of acetylcholine.
Physostigmine - an overview | ScienceDirect Topics
Physostigmine is an acetylcholinesterase inhibitor that increases muscle contraction through its action at the neuromuscular junction. Physostigmine was given as an overnight infusion to patients with moderate to severe OSA in a placebo-controlled, randomized trial.
Safety and effectiveness of physostigmine: a 10-year ... - PubMed
Background: Physostigmine has long been recognized as an antidote to reverse anticholinergic delirium. However, its effectiveness, safety profile, and dosing have been disputed. Objectives: To describe effectiveness, adverse events, and dosing associated with the use of physostigmine to reverse anticholinergic delirium.