The interleukin-2 receptor in human monocytes and macrophages ...
Human monocytes constitutively express the intermediate-affinity interleukin-2 receptor (IL2R) p75, while freshly isolated monocytes lack the low-affinity IL2R p55 (Tac antigen, CD25).
Biology and regulation of IL-2: from molecular mechanisms to …
2018年8月8日 · With the cloning of IL-2 receptor α-chain (IL-2Rα, encoded by IL2RA; also known as CD25) 5,6 and then IL-2Rβ (encoded by IL2RB; also known as CD122) 7, it became clear …
The IL-2 – IL-2 receptor pathway: Key to understanding multiple ...
For instance, T h 1-cells activate macrophages and cytotoxic T-cells (T c; CD8 +). T h 2-cells trigger B-cells to produce auto-antibodies against myelin sheaths, axons and …
CXCL9, IL2RB, and SPP1, potential diagnostic biomarkers in the co ...
2024年7月16日 · This study demonstrates that CXCL9, IL2RB, and SPP1 may serve as potential biomarkers for the diagnosis of the co-morbidity patterns of AS and NASH and as potential …
IL2RB - 维基百科，自由的百科全书
白介素-2受体β亚基（Interleukin-2 receptor subunit beta，缩写IL2RB）也称为“白介素-15受体β亚基”（IL15RB）、P70-75、分化簇122（CD122，cluster of differentiation 122）是一种细胞表 …
IL2RB - an overview | ScienceDirect Topics
the growth and differentiation of monocyte precursors of macrophages, and it stimulates the increase of the tumoricidal effect of macrophages by antibody-dependent cellular cytotoxicity …
Interleukin-2 and human monocyte activation - PubMed
The recognition of the monocyte/macrophage-activating properties of IL-2 has broadened our image of the biological effects of this lymphokine from those of a T cell growth factor to those …
A novel human IL2RB mutation results in T and NK cell–driven …
In summary, we have identified a novel primary immunodeficiency disease caused by the first described human IL2RB mutation, revealing previously unappreciated insights into IL-2/15 …
Interleukin 2 receptor subunit beta as a novel hub gene plays a ...
2022年6月15日 · IL2RB is an immune-related hub gene and a potential hub gene with significant diagnostic value in AAA. Abdominal aortic aneurysm (AAA) is potentially life threatening and …
Entry - *146710 - INTERLEUKIN 2 RECEPTOR, BETA; IL2RB - OMIM
2019年7月9日 · The IL2RB gene encodes the beta subunit of the interleukin-2 (IL2) receptor, which transmits signals from the cytokines IL2 (147680) and IL15 (600554). IL2RB shows …