Dynamic urea bond for the design of reversible and self-healing ...
2014年2月4日 · Here we report the rational design of hindered urea bonds (urea with bulky substituent attached to its nitrogen) and the use of them to make polyureas and poly (urethane-urea)s capable of...
Hindered urea bonds for dynamic polymers: An overview
2021年2月1日 · Polymers with hindered urea bonds are degradable and hydrolysable. Polymers bearing dynamic covalent bonds have gained great attention over the last decades owing to their self-healing, shape memory, and environmental adaptation properties.
Intrinsic self-healing polymers with a high E -modulus based
2017年8月18日 · Commercially available monomers are polymerized using light-induced polymerization, resulting in networks crosslinked by hindered urea molecules. These moieties are reversible and, thus, can be...
In this study, we report the design of polyureas bearing hindered urea bonds (HUBs) as potentially one of the least expensive degradable polymers that can be easily synthesized by mixing multifunctional bulky amines and isocyanates, expanding the family of hydrolyzable polymers.
Dynamic multiphase semi-crystalline polymers based on …
2019年10月18日 · Here, we present the reversible pyrazole–urea bonds (PzUBs), which are applied for the design of a series of mechanically robust dynamic polymers, poly(pyrazole–ureas) (PPzUs).
PEGylated Polyurea Bearing Hindered Urea Bond for Drug …
2019年4月18日 · Polyureas bearing hindered urea bonds (HUBs) are able to be synthesized by the reaction between the monomers with diisocyanate or diamine groups [1, 2]. As the orbital coplanarity of the amide bonds can be disturbed [3], HUBs are hydrolyzable, and the hydrolytic products are biologically safe [4].
Hindered urea bonds for dynamic polymers: An overview
This work reports the first design of hydrolyzable polyureas bearing dynamic hindered urea bonds (HUBs) that can reversibly dissociate to bulky amines and isocyanates, the latter of which can be further hydrolyzed by water, driving the equilibrium to facilitate the degradation ofpolyureas.
Hydrolyzable polyureas bearing hindered urea bonds.
2014年11月26日 · Here, we report the first design of hydrolyzable polyureas bearing dynamic hindered urea bonds (HUBs) that can reversibly dissociate to bulky amines and isocyanates, the latter of which can be further hydrolyzed by water, driving the equilibrium to facilitate the degradation of polyureas.
PEGylated Polyurea Bearing Hindered Urea Bond for 2 Drug …
This work reports the first design of hydrolyzable polyureas bearing dynamic hindered urea bonds (HUBs) that can reversibly dissociate to bulky amines and isocyanates, the latter of which can be further hydrolyzed by water, driving the equilibrium to facilitate the degradation ofpolyureas.
Hindered Urea Bond: A Bilaterally Responsive Chemistry to …
2018年12月5日 · The hindered urea bond, a type of dynamic covalent bond which can reversibly dissociate into isocyanate and amine, responds to hydrogen peroxide in two opposing ways: Perhydrolysis of isocyanate and oxidation of amine lead to the bond fracture; while formation of a urethane product with an oxygen inserted into the original urea structure gives ...