Disulfiram-like drug - Wikipedia
A disulfiram-like drug is a drug that causes an adverse reaction to alcohol leading to nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover-like symptoms among others.
Disulfiram-like Reaction & Others [+ Cheat Sheet] | Lecturio
2024年10月9日 · What are disulfiram-like reactions? A disulfiram-like reaction occurs when a medication other than disulfiram, which is used in treatment of alcohol use disorder, provokes similar symptoms when combined with alcohol. Symptoms: Severe flushing; Anxiety; Sweating; Abdominal cramping; Tachycardia; Hypotension; Common trigger medications include:
UMEM Educational Pearls - University of Maryland School of …
2008年8月7日 · There are a number of medications that produce the disulfiram-like reaction when ingested with alcohol. The disulfiram reaction is a very uncomfortable reaction characterized by severe flushing, and may be accompanied by tachycardia and hypotension.
Pharmaceutical agents known to produce disulfiram-like reaction ...
According to our findings, metronidazole and quinacrine do not produce a typical disulfiram-like reaction, because they do not inhibit hepatic aldehyde dehydrogenase nor increase blood acetaldehyde. Moreover, all tested agents share the common property to enhance brain serotonin, whereas a respective effect of ethanol is well established.
79: Disulfiram and Disulfiramlike Reactions - McGraw Hill Medical
In considering disulfiram toxicity, a distinction must be made between the clinical manifestations of a disulfiram–ethanol reaction and the toxic effects of disulfiram itself. Direct disulfiram toxicity can be further classified as ...
Pharmaceutical Agents Known to Produce Disulfiram-Like Reaction ...
Various therapeutic agents have been found to produce untoward effects when combined with ethanol, which often are reported as disulfiram-like reaction. Among other drugs, chloramphenicol, metronidazole, furazolidone, and quinacrine have been demonstrated to bring about such a reaction (Edwards, Fink, and Van-Dyke 1986; Fried 1980; Uri and ...
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The author summarized the mechanism,related factors and the advances in clinical medication of disulfiram-like reaction by searching the literatures,in order to provide references for clinical prevention and treatment.
Disulfiram effect - WikEM
Disulfiram (Trade names: Antabuse, Antabus) - causes an acute reaction in the presence of ethanol. Works by inhibiting acetaldehyde dehydrogenase → buildup of acetaldehyde → unpleasant effects. Designed to assist in alcohol cessation. …
emDOCs.net – Emergency Medicine EducationTOXCard: Disulfiram Reaction …
2019年2月6日 · What is the disulfiram reaction? What common agents can induce a disulfiram-like reaction? Is there an antidote for the disulfiram reaction? Disulfiram tetraethylthiuram disulfide (TETD) was the first western medication used to treat alcohol dependence and in 1951 was approved by the Food and Drug Administration as a treatment for alcoholism. (1)
List of Drugs that may cause 'Disulfiram like reaction' - Medindia
2023年11月16日 · This page lists all known medications that could potentially lead to 'Disulfiram like reaction' as a side effect. It's important to note that mild side effects are quite common with...