Vancomycin Calculator - ClinCalc.com
This vancomycin calculator uses pharmacokinetic population estimates, Bayesian modeling, and the Sawchuk-Zaske method to calculate a vancomycin dosing regimen for an adult patient. Vancomycin regimens can be calculated both empirically (without any prior doses) or using one or two vancomycin levels.
Vancomycin AUC:MIC versus T>MIC - ClinCalc.com
Vancomycin as AUC:MIC. More recently, AUC:MIC has emerged as a proposed alternative to the T>MIC theory. The primary basis of AUC:MIC theory stems from a neutropenic mouse model, 1 where AUC:MIC better correlated to bacterial killing compared to T>MIC.
Vancomycin Calculator - ClinCalc.com
This vancomycin calculator uses a variety of published pharmacokinetic equations and principles to estimate a vancomycin dosing regimen for a patient. A regimen can be completely empiric, where the vancomycin dose is based on body weight and creatinine clearance, or a regimen may be calculated based on one or more vancomycin levels.
vancomycin - ClinCalc.com
2012年4月7日 · Current evidence suggests that the vancomycin AUC:MIC ratio is the most important pharmacodynamic parameter associated with treatment success. 1 Given that current guidelines recommend an AUC:MIC ratio of at least 400, a plateau of 20-25 mcg/mL (20 mcg/mL * 24 hrs) would provide an AUC:MIC ratio > 400 for isolates with an MIC of 1-1.5 mcg/mL.
The Evidence behind Continuous-Infusion Vancomycin Therapy
Current evidence suggests that the vancomycin AUC:MIC ratio is the most important pharmacodynamic parameter associated with treatment success. 1 Given that current guidelines recommend an AUC:MIC ratio of at least 400, a plateau of 20-25 mcg/mL (20 mcg/mL * 24 hrs) would provide an AUC:MIC ratio > 400 for isolates with an MIC of 1-1.5 mcg/mL.
Search Results vancomycin - ClinCalc.com
2015年6月7日 · Vancomycin AUC:MIC versus T>MIC There is a significant amount of controversy regarding the most appropriate therapeutic goal for vancomycin therapy. The difference of opinion stems from the pharmacodynamic activity of vancomycin.
AUC:MIC - ClinCalc.com
2012年4月7日 · The difference of opinion stems from the pharmacodynamic activity of vancomycin. Definitions. MIC (minimum inhibitory concentration) – The minimum concentration of antibiotic to inhibit the growth of an organism. AUC (area under the curve) – The total exposure of an antibiotic to an organism Continue reading →
Vancomycin - ClinCalc
Advanced vancomycin pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods, including Bayesian modeling, to determine the optimal vancomycin dose.
therapeutic drug monitoring - ClinCalc.com
2011年12月9日 · Current evidence suggests that the vancomycin AUC:MIC ratio is the most important pharmacodynamic parameter associated with treatment success. 1 Given that current guidelines recommend an AUC:MIC ratio of at least 400, a plateau of 20-25 mcg/mL (20 mcg/mL * 24 hrs) would provide an AUC:MIC ratio > 400 for isolates with an MIC of 1-1.5 mcg/mL.
Aminoglycoside Calculator – Now Available! - ClinCalc.com
Familiar interface based on the extremely popular vancomycin calculator; Empirically dose an aminoglycoside based on extended-interval or conventional dosing; Built-in extended-interval nomograms, including the Hartford, Barnes-Jewish, Rochester, and Urban-Craig methods