Stem-loop - Wikipedia
A stem-loop occurs when two regions of the same nucleic acid strand, usually complementary in nucleotide sequence, base-pair to form a double helix that ends in a loop of unpaired nucleotides. Stem-loops are most commonly found in RNA, and are a key building block of many RNA secondary structures.
Stem-loop (Hairpin loop): Properties, Types, Examples, Uses
May 15, 2024 · What is a stem-loop (hairpin loop)? A Stem-loop can be defined as a hairpin-like pattern formed because of the intramolecular base pairing of the nucleotide sequence (especially in palindromic sequence) within the same molecule.
Stem-Loop - an overview | ScienceDirect Topics
Aug 28, 2012 · Hairpin or stem-loop is a commonly observed secondary structure of RNA where A, U, G, C nucleotides form hydrogen bonds with complementary nucleotides on a wrinkled or folded back segment of the same strand (Svoboda & …
The Role of the Stem-Loop A RNA Promoter in Flavivirus Replication
Jun 9, 2021 · In flaviviruses, the 5′-end of the viral RNA genome contains a 70 nucleotide-long stem-loop, called stem-loop A (SLA), which functions as a promoter for genome replication. During replication, flaviviral polymerase NS5 specifically recognizes SLA to both initiate viral RNA synthesis and to methylate the 5′ guanine cap of the nascent RNA.
Specific length and structure rather than high thermodynamic …
Feb 21, 2022 · Translating ribosomes unwind mRNA secondary structures by three basepairs each elongation cycle. Despite the ribosome helicase, certain mRNA stem-loops stimulate programmed ribosomal frameshift...
Stems and Loops - SpringerLink
Apr 28, 2016 · All types of RNA fold into highly significant (non-random) ‘stem-loop’ structures. While the selective forces affecting tRNA and rRNA structures mainly relate to their roles in the cytoplasm, those affecting mRNA structures largely relate to the need for structure (stem-loop potential) of the genes from which they were transcribed.
Hairpin Structure - SpringerLink
Hairpin structures occur in pre-microRNA structures and most famously in transfer RNA, which contain three true stem-loops and one stem that meet in a cloverleaf pattern. The anticodon that recognizes a codon during the translation process is located on …
Stem-loop oligonucleotides: a robust tool for molecular biology …
Jun 1, 2002 · The specific structural features of stem-loop (hairpin) DNA constructs provide increased specificity of target recognition. Recently, several robust assays have been developed that exploit the potential of structurally constrained …
Stem-Loop - an overview | ScienceDirect Topics
The dominant structural element that results is the hairpin loop, or stem-loop, which is produced when an RNA chain folds back on itself so that complementary sequences close to each other in its sequence can pair.
Chromosome Structure II: Stem-loops and Circle-loops - eLife
Jun 20, 2024 · Key to understanding the 3D organization of chromosomes in multicellular eukaryotes will be the identification of TADs that are stem-loops and TADs that are circle-loops. In the studies reported here, we have used MicroC to analyze the contact maps generated by stem-loops and circle-loops.