SMA (Spinal Muscular Atrophy): What It Is, Symptoms & Types
2024年6月6日 · Spinal muscular atrophy (SMA) is a genetic condition that causes worsening muscle weakness. There are five subtypes, which range in severity and age of onset. There’s no cure for SMA, but certain therapies and medications can help manage symptoms.
Spinal Muscular Atrophy | National Institute of Neurological Disorders …
2024年7月30日 · Spinal muscular atrophy (SMA) refers to a group of hereditary diseases which affect motor neurons. Motor neurons are specialized nerve cells in the brain and spinal cord that control movement in the arms, legs, face, chest, throat, and tongue, as well as skeletal muscle activity, including muscles used for speaking, walking, swallowing, and ...
Spinal muscular atrophy - Wikipedia
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. [3] [4] [5] It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. [6]
Spinal Muscular Atrophy (SMA) - Johns Hopkins Medicine
Spinal muscular atrophy (SMA) is a disorder affecting the motor neurons—nerve cells that control voluntary muscle movement. These cells are located in the spinal cord. Because the muscles cannot respond to signals from the nerves, they atrophy — weaken and shrink — from inactivity.
Spinal Muscular Atrophy (SMA) - Diseases - Muscular Dystrophy Association
SMA involves the loss of nerve cells called motor neurons in the spinal cord and is classified as a motor neuron disease. In the most common form of SMA (chromosome 5 SMA, or SMN-related SMA), there is wide variability in age of onset, symptoms, and rate of progression.
Spinal Muscular Atrophy: Causes, Symptoms, and Treatment - WebMD
2023年4月8日 · Spinal muscular atrophy (SMA) most often affects babies and children and makes it hard for them to use their muscles. When your child has SMA, there's a breakdown of the nerve cells in the...
Spinal muscular atrophy - MedlinePlus
Spinal muscular atrophy is a genetic disorder characterized by weakness and wasting in muscles used for movement (skeletal muscles). It is caused by a loss of specialized nerve cells, called motor neurons that control muscle movement.
Spinal Muscular Atrophy (SMA) - Children's Hospital of Philadelphia
Spinal muscular atrophy (SMA) is a genetic disease that affects the spinal cord and nerves, resulting in muscle wasting and weakness. Untreated, it is a neurodegenerative, progressive disease, which can be fatal in its more severe forms.
Spinal Muscular Atrophy - Symptoms, Causes, Treatment | NORD
2024年4月17日 · Spinal muscular atrophy (SMA) is a group of inherited neuromuscular disorders characterized by loss of nerve cells in the spinal cord called lower motor neurons or anterior horn cells.
Spinal Muscular Atrophy (SMA) - Penn Medicine
Spinal muscular atrophy (SMA) is a group of disorders of the motor neurons (motor cells). These disorders are passed down through families (inherited) and can appear at any stage of life. The disorder leads to muscle weakness and atrophy. Werdnig-Hoffmann disease; Kugelberg-Welander disease.