Choosing a Drug to Prevent Malaria | Malaria | CDC
2024年7月18日 · Primaquine. Begin 1 – 2 days prior to travel, daily during travel, and for 7 days after leaving. Adults: 30 mg base (52.6 mg salt), daily. Children: 0.5 mg/kg base (0.8 mg/kg salt) up to adult dose daily
When taking primaquine for the prevention of malaria on a short trip, both adults and children should take one dose of primaquine per day starting a day or two before traveling to the area where malaria transmission occurs. They should take one dose per day while there, and for 7 consecutive days after leaving.
Primaquine - Wikipedia
Primaquine is a medication used to treat and prevent malaria and to treat Pneumocystis pneumonia. [2] Specifically it is used for malaria due to Plasmodium vivax and Plasmodium ovale along with other medications and for prevention if other options cannot be used. [2] It is an alternative treatment for Pneumocystis pneumonia together with clindamycin. [2] …
Primaquine in vivax malaria: an update and review on …
Abstract. Primaquine was officially licensed as an anti-malarial drug by the FDA in 1952. It has remained the only FDA licensed drug capable of clearing the intra-hepatic schizonts and hypnozoites of Plasmodium vivax.This update and review focuses on five major aspects of primaquine use in treatment of vivax malaria, namely: a) evidence of efficacy of primaquine for its current indications; b ...
Primaquine: the risks and the benefits - Malaria Journal
2014年11月3日 · Primaquine is the only generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the only potent gametocytocide in falciparum malaria.
Primaquine: Uses, Interactions, Mechanism of Action - DrugBank …
Primaquine is an antimalarial agent and is the essential co-drug with chloroquine in treating all cases of malaria. In the blood, malaria parasites break down a part of the red blood cells known as haemoglobin.
Primaquine (oral route) - Mayo Clinic
2024年2月29日 · Primaquine is used to treat malaria and prevents it from coming back after treatment (relapse). Primaquine belongs to a group of medicines, called antiprotozoals. It works by treating malaria, a red blood cell infection transmitted by the bite of a mosquito.
Primaquine for uncomplicated - The Lancet
2024年9月24日 · Primaquine, the only widely available treatment to prevent relapsing Plasmodium vivax malaria, is produced as 15 mg tablets, and new paediatric formulations are being developed.
Efficacy of 8-aminoquinolines for - The Lancet
2 天之前 · In a study in 1952, 4 primaquine was administered to 699 White participants in a 10–240 mg daily dose. It was concluded that at doses of 15 mg the drug could be safely administered daily for 2 weeks without medical supervision. Doses as high as 30 mg per day required an outpatient clinic follow-up, and weekly 30 mg doses for as long as 52 ...
WHO prequalifies diagnostic test to support safer administration …
2025年1月8日 · Testing devices that can accurately distinguish patients with G6PD activity levels above and below the normal levels provide critical information to clinicians to decide which of P. vivax anti-relapse treatment regimens is most appropriate, including low- and high-dose primaquine and single-dose tafenoquine.