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L1, also known as L1CAM, is a transmembrane protein member of the L1 protein family, encoded by the L1CAM gene. This protein, of 200 to 220 kDa, is a neuronal cell adhesion molecule with a strong implication in cell migration, adhesion, neurite outgrowth, myelination and neuronal differentiation. It also plays a key … 展开
L1 protein is located all over the nervous system on the surface of neurons. It is placed along the cellular membrane so that one end of the protein remains inside the nerve cell while the other end stays on the outer surface of the … 展开
The L1 cell adhesion molecule (L1CAM) is a cell surface glycoprotein found in humans (and other forms of life as mice, for example) which has a … 展开
The gene that regulates L1CAM transcription is found in chromosome X. The L1CAM gene is 24,657 bp in length, and is made up of 28 … 展开
L1CAM has three different isoforms, that differ in their amino acid sequency, because of alternative splicing (a process that allows obtaining different mRNA mature molecules from one primary transcript of mRNA). L1CAM isoform 1 is known as the 展开
The human L1CAM gene is found in X chromosome regions that are implicated in different neuromuscular diseases, and near the one associated with mental retardation. The L1CAM … 展开
L1 is an important protein for the development of the nervous system affecting both cell adhesion and motility.
Cell adhesion
L1 has a static function as a cell adhesion molecule which connects different cells. It is involved in the 展开CC-BY-SA 许可证中的维基百科文本 L1 (Protein) - an overview | ScienceDirect Topics
2012年1月13日 · L1 is a protein of about 55 kDa and is termed as the major capsid protein, being particularly abundant and representing 80% of the capsid proteins (ratio L1/L2 10:1) …
Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution …
2016年8月8日 · Ubiquitin C-terminal hydrolase L1 (UCH-L1) is an extremely abundant protein in the brain where, remarkably, it is estimated to make up 1–5% of total neuronal protein. …
L1 (Protein) - an overview | ScienceDirect Topics
The L1 protein is the major capsid protein crucial for viral attachment and entry and is capable of forming virus-like particles on its own. The L1 protein is highly immunogenic and is expressed …
LINE-1 transcription activates long-range gene expression
2024年6月7日 · Long interspersed nuclear element-1 (LINE-1 or L1) is a retrotransposon group that constitutes 17% of the human genome and shows variable expression across cell …
L1 family - Wikipedia
The L1 family is a family of cell adhesion molecules that includes four different L1-like proteins. They are members of the immunoglobulin superfamily . The members of the L1-family in …
LINE-1 protein localization and functional dynamics during the cell ...
2018年1月8日 · Here we identify modes of L1 proteins' entrance into the nucleus, a necessary step for L1 proliferation. Using functional, biochemical, and imaging approaches, we also show …
LINE-1 protein localization and functional dynamics during the cell ...
2018年1月8日 · LINE-1/L1 retrotransposon sequences comprise 17% of the human genome. Among the many classes of mobile genetic elements, L1 is the only autonomous …
L1 (Protein) - an overview | ScienceDirect Topics
We have isolated from human leukocytes a protein, provisionally called L 1, and established immunological methods for its detection in tissues, plasma and other body fluids. By …
The papillomavirus major capsid protein L1 - PubMed
Recombinant L1 proteins can spontaneously self-assemble into a highly immunogenic structure that closely mimics the natural surface of native papillomavirus virions. This has served as the …
