Epigenetics of Meningiomas - PMC - National Center for …
2015年5月25日 · Altered DNA methylation, microRNA expression, histone, and chromatin modifications are frequently noted in meningiomas bearing prognostic and therapeutic relevance. In this review we provide an overview on recently identified epigenetic alterations in meningiomas and discuss their role in tumour initiation, progression, and recurrence.
Epigenetics of Meningiomas - PubMed
Altered DNA methylation, microRNA expression, histone, and chromatin modifications are frequently noted in meningiomas bearing prognostic and therapeutic relevance. In this review we provide an overview on recently identified epigenetic alterations in meningiomas and discuss their role in tumour initiation, progression, and recurrence.
Epigenetics of Meningiomas - Murnyák - 2015 - Wiley Online …
2015年5月25日 · Altered DNA methylation, microRNA expression, histone, and chromatin modifications are frequently noted in meningiomas bearing prognostic and therapeutic relevance. In this review we provide an overview on recently identified epigenetic alterations in meningiomas and discuss their role in tumour initiation, progression, and recurrence.
The Epigenetic Landscape of Meningiomas | SpringerLink
2023年7月12日 · The study of epigenetic changes in meningiomas has played a significant role in uncovering factors that contribute to tumor pathogenesis and progression, and have produced robust, molecular classification systems.
The Epigenetic Landscape of Meningiomas - PubMed
Some examples of these alterations that have been studied in meningiomas include DNA methylation, microRNA interaction, histone packaging, and chromatin restructuring. In this chapter we will describe in detail each of these mechanisms of epigenetic modification in meningiomas and their prognostic significance.
Epigenetic dysregulation in meningiomas - PMC - National …
2022年6月6日 · These studies provide insight into the patterns of epigenetic dysregulation in meningiomas and characterized epigenetic changes that are common across methylation clusters. In particular, all tumor subtypes exhibited hypomethylation affecting the promoter of the transcription factor FOXC1 and its upstream lncRNA transcript FOXCUT.
Genetic and epigenetic alterations in meningiomas - ScienceDirect
2017年7月1日 · Epigenetic alterations in meningiomas include hypermethylation of the tumor suppressor genes p73 in grade I meningiomas and TIMP3 GSTP1, MEG3, HOXA6, HOXA9, PENK, WNK2 and UPK3A genes with an increasing frequency according to grade.
[PDF] Epigenetics of Meningiomas - Semantic Scholar
2015年5月25日 · An overview on recently identified epigenetic alterations in meningiomas is provided and their role in tumour initiation, progression, and recurrence is discussed. Meningiomas account for one-third of all adult central nervous system tumours and are divided into three WHO grades.
Advances in meningioma genomics, proteomics, and epigenetics…
2020年12月12日 · A combination of epigenetics, mRNA along with genomics and proteomics will allow for a meningioma biomarker panel to predict aggressive meningiomas exhibiting high rates of progression or recurrence (Figure 1). Abnormalities ranging from altered DNA methylation, miRNA expression and chromatin restructuring involved in the genesis of meningiomas ...
(PDF) Epigenetics of Meningiomas - ResearchGate
2015年5月25日 · Indeed, growing body of evidence suggests that disturbed epigenetic regulation plays a key role in the pathogenesis of meningiomas. Altered DNA methylation, microRNA expression, histone, and...
- 某些结果已被删除