Deoxyribose - an overview | ScienceDirect Topics
Deoxyribose is the same sugar found in RNA, but with oxygen removed from the 2′ carbon position. • Nucleotide is made up of a phosphate group, a pentose sugar (deoxyribose), and a nitrogenous base. • The phosphodiester bond • The phosphate group is bond to the nucleoside at the hydroxyl group of the 5′ carbon atom of deoxyribose. •
Deoxyribose - an overview | ScienceDirect Topics
The ability of a substance to inhibit deoxyribose degradation under these reaction conditions is a measure of its ability to interfere with site-specific Fenton chemistry. When ascorbate is omitted from the deoxyribose reaction mixture, the ability of added compounds to reduce the Fe 3+ –EDTA complex can be tested. This gives an index of pro ...
Deoxyribose - an overview | ScienceDirect Topics
The bases are identified by A, T, G, and C, whereas the deoxyribose groups are identified by dR. Two hydrogen bonds form between dA and dT; three form between dC and dG. This bonding occurs between bases on opposite strands of the double helix. During RNA synthesis (transcription), the DNA strands are separated.
Deoxyribose - an overview | ScienceDirect Topics
Deoxyribose is present at limiting concentrations in the contents of the mouse cecum. The potential role of deoxyribose catabolism in the colonization of the mammalian intestine by pathogenic E. coli isolates was therefore investigated using the streptomycin-treated mouse model of intestinal colonization.
2 Deoxyribose - an overview | ScienceDirect Topics
A well-known example is 2-deoxyribose, which is a component of deoxyribonucleotides, the repeating units of deoxyribonucleic acids (DNA). Another example is L-fucose (6-deoxyl-L-galactose), a constituent of cell membrane glycoproteins and glycolipids and one of the few monosac-charides that exist in the L-configuration ( Figure 9-17 ).
Why deoxyribose for DNA and ribose for RNA?
2014年12月13日 · The absence of one Oxygen is the key for extending DNA's longevity. When the 2' Oxygen is absent in deoxyribose, the sugar molecule is less likely to get involved in chemical reactions( the aggressive nature of Oxygen in chemical reactions are famous). So by removing the Oxygen from deoxyribose molecule, DNA avoids being broken down. In an RNA ...
2 Deoxyribose - an overview | ScienceDirect Topics
Deoxyribonucleic acid (DNA) is made up of sugar, a nitrogenous base and a phosphate group (Figure 1.2). The combination of these molecules makes the building blocks for the DNA synthesis. The sugar present in the DNA is 2’deoxyribose, a five carbon monosaccharide, which is devoid of oxygen in its 2’ position, hence the name deoxyribonucleic ...
5-Deoxyribose Phosphate - an overview | ScienceDirect Topics
5-Deoxyribose Phosphate. In subject area: Chemistry. 5-Deoxyribose Phosphate is a compound involved in the catabolism of deoxyribose from nucleic acids, primarily catalyzed by the enzyme Deoxyribose-5-phosphate aldolase (DERA) found in various organisms. AI generated definition based on: Comprehensive Natural Products Chemistry, 1999.
Deoxyribose - an overview | ScienceDirect Topics
Anna Karlsson, in Pharmacology & Therapeutics, 2003. Deoxyribonucleotides and ribonucleotides are the building blocks of DNA and RNA, respectively. Both nucleotides are built up by a nitrogen ring-structured base, a pentose sugar (deoxyribose or ribose), and a phosphate group. DNA is replicated by enzymes known as DNA polymerases.
The deoxyribose method: A simple “test-tube” assay for …
1987年8月15日 · The rate of deoxyribose degradation was constant over the 1-h incubation period. The rate of deoxyribose degradation may be increased by including a reducing agent, such as ascorbic acid (16), in the reaction mixture: Fe 3+-EDTA + ascorbate - Fe Z+-EDTA + oxidized ascorbate. [6] Addition of extra H202 may also accelerate the rate (16,17).