Catenin beta-1 - Wikipedia
Catenin beta-1, also known as β-catenin (beta-catenin), is a protein that in humans is encoded by the CTNNB1 gene. β-Catenin is a dual function protein , involved in regulation and coordination of cell–cell adhesion and gene transcription .
CTNNB1 Gene - GeneCards | CTNB1 Protein | CTNB1 Antibody
2024年10月1日 · GeneCards Summary for CTNNB1 Gene. CTNNB1 (Catenin Beta 1) is a Protein Coding gene. Diseases associated with CTNNB1 include Pilomatrixoma and Colorectal Cancer. Among its related pathways are Signaling by CTNNB1 phospho-site mutants and Gastrulation.
Wnt/β-catenin signalling: function, biological mechanisms ...
2022年1月3日 · The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin signalling often...
The regulation of β-catenin activity and function in cancer ...
2017年5月5日 · The activity of β-catenin is under the control of several highly regulated processes, including ligand–receptor interactions, β-catenin stability, β-catenin nuclear translocation and β-catenin transcriptional activity.
The Role of the Wnt/β-catenin Signaling Pathway in Formation ...
Catenin, beta 1 (β-catenin; Ctnnb1) was first named in the late 1980s by Ozawa and colleagues along with α-catenin and γ-catenin as these proteins linked E-cadherin to cytoskeletal structures in Ca 2+-dependent cell adhesion (Ozawa et al., 1989).
CTNNB1 catenin beta 1 [Homo sapiens (human)] - Gene - NCBI
5 天之前 · Summary. The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells.
Beta-Catenin - an overview | ScienceDirect Topics
The catenin (cadherin-associated protein), beta 1, 88 kD (CTNNB1) gene spans 65 K and encodes β-catenin, a key transcription factor of the Wnt-signaling pathway. Beta-catenin is involved in osteoblast differentiation from mesenchymal stem cells …