Cancer Stem Cells: From an Insight into the Basics to Recent …
网页Small subpopulations of cancer cells that are long-lived with the potential of excessive self-renewal and tumor formation are called cancer stem cells (CSCs) or cancer-initiating cells or tumor stem cells.
Cancer stem cells: advances in knowledge and implications for cancer …
网页2024年7月5日 · Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor...
Targeting cancer stem cell pathways for cancer therapy
网页2020年2月7日 · Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been considered promising therapeutic targets for cancer therapy.
Clinical and Therapeutic Implications of Cancer Stem Cells
网页2019年6月5日 · Normal stem cells and their cancer stem-cell counterparts protect themselves from toxins and genotoxic stress through multiple mechanisms, including increased expression of DNA-repair...
Cancer stem cells - Latest research and news | Nature
网页2024年9月26日 · Cancer stem cells are rare immortal cells within a tumour that can both self-renew by dividing and give rise to many cell types that constitute the tumour, and can therefore form...
A Concise Review: The Role of Stem Cells in Cancer Progression …
网页2021年4月20日 · The properties of cancer stem cells (CSCs) have recently gained attention as an avenue of intervention for cancer therapy. In this review, we highlight some of the key roles of CSCs in altering the cellular microenvironment in favor of cancer progression.
Cancer and stem cells - PMC - National Center for Biotechnology …
网页2021年4月5日 · The stem cell origin of cancer. A comprehensive understanding of the origin of cancer cells is critical for designing effective strategies to treat or prevent cancer, as well as for guiding the risk assessment of cancer.
Cancer stem cells: Recent insights and therapies - ScienceDirect
网页2023年3月1日 · Cancer stem cells: Recent insights and therapies. Author links open overlay panel. Hongyu Zhou a. , Licheng Tan a. , Beilei Liu a b. , Xin-Yuan Guan a b c d e. Show more. Add to Mendeley. Share. https://doi.org/10.1016/j.bcp.2023.115441 Get rights and content. Abstract.
Hallmarks of cancer stemness: Cell Stem Cell - Cell Press
网页2024年5月2日 · Cancer stemness, regarded as a crucial factor in tumor development, has been recognized to involve a plastic cellular state influenced by dynamic interactions between cancer stem cells (CSCs) and their niche. Herein, we provide a summary of the defining and emerging hallmarks of CSCs and/or cancer stemness.
Stem cells and cancer | Harvard Stem Cell Institute (HSCI)
网页Lurking somewhere within every tumor, some say, are a few stem cells that have lost their genetic marbles, so to speak - continuously supplying a malignant mass with cancerous cells. Stem cells are key to our normal development and …
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