CD55 Gene - GeneCards | DAF Protein | DAF Antibody
2024年8月5日 · CD55 (CD55 Molecule (Cromer Blood Group)) is a Protein Coding gene. Diseases associated with CD55 include Complement Hyperactivation, Angiopathic Thrombosis, And Protein-Losing Enteropathy and Blood Group, Cromer System .
Beyond the Role of CD55 as a Complement Component - PMC
2018年2月20日 · Decay-accelerating factor (DAF or CD55) is a known inhibitor of the complement system and has recently attracted substantial attention due to its role in various diseases, such as cancer, protein-losing enteropathy, and malaria.
CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and Thrombosis
2017年7月6日 · We identified homozygous loss-of-function mutations in the gene encoding CD55 (decay-accelerating factor), which lead to loss of protein expression. Patients’ T lymphocytes showed increased...
CD55 in cancer: Complementing functions in a non-canonical …
2022年12月28日 · CD55, or decay accelerating factor, is a membrane lipid microdomain-associated, GPI-anchored protein implicated in the shielding of cells from complement-mediated attack via accelerating decay of C3 and C5.
Mapping CD55 Function - Journal of Biological Chemistry
Decay-accelerating factor (CD55), a regulator of the alternative and classical pathways of complement activation, is expressed on all serum-exposed cells. It is used by pathogens, including many enteroviruses and uropathogenic Escherichia coli, as a receptor prior to infection.
CD55 Is Essential for CD103 - National Center for Biotechnology …
Decay-accelerating factor (DAF; or CD55) is an intrinsic cellular regulator originally characterized as a control protein that circumvents activation of systemic complement on self-cell surfaces. 15 Recently, DAF has been found to modulate T-cell responses. 16, 17 Mechanistic understanding of its T-regulatory function came from the discovery 18 ...
CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and ... - PubMed
2017年7月6日 · CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy (the CHAPLE syndrome) is caused by abnormal complement activation due to biallelic loss-of-function mutations in CD55.
Beyond the Role of CD55 as a Complement Component
2018年2月20日 · Decay-accelerating factor (DAF or CD55) is a known inhibitor of the complement system and has recently attracted substantial attention due to its role in various diseases, such as cancer, protein-losing enteropathy, and malaria.
CD55 CD55 molecule (Cromer blood group) [ (human)]
2024年4月30日 · CD55 is an essential host factor for P. falciparum invasion. CD55-null erythrocytes were refractory to invasion by all isolates of P. falciparum because parasites failed to attach properly to the erythrocyte surface.
Protein-Losing Enteropathy | New England Journal of Medicine
2023年8月23日 · CD55 is a cell-surface regulator of the C3 complement convertase, and genetic loss of the CD55 protein causes complement-mediated damage and blockade of the lymphatic vessels and intestinal ...
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