Basigin - Wikipedia
网页Basigin (BSG) also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the BSG gene. [5] [6] [7] This protein is a determinant for the Ok blood group system.
新冠靶点新视角四：跨膜糖蛋白CD147 - 知乎 - 知乎专栏
网页cd147与神经系统：cd147表达于血脑屏障内皮细胞、脉络膜上皮细胞和视网膜色素上皮细胞，可作为血脑屏障的标志物，与人体正常血脑屏障的功能相关。cd147分子可参与神经元与神经胶质细胞的相互作用。
CD147: a novel modulator of inflammatory and immune disorders
网页CD147, a transmembrane glycoprotein, is expressed on all leukocytes, platelets, and endothelial cells. It has been implicated in a variety of physiological and pathological activities through interacting with multiple partners, including cyclophilins, monocarboxylate transporters, Caveolin-1, and in ….
CD147 antibody specifically and effectively inhibits infection …
网页2021年9月25日 · Mechanistically, we proposed that severe COVID-19-related cytokine storm is induced by a “spike protein-CD147-CyPA signaling axis”: Infection of SARS-CoV-2 through CD147 initiated the JAK-STAT...
Basigin (CD147), a multifunctional transmembrane glycoprotein with ...
网页2015年12月18日 · Basigin, also called CD147 or EMMPRIN, is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily. Basigin has isoforms; the common form (basigin or basigin-2) has two immunoglobulin domains, and the extended form (basigin-1) has three.
战疫时刻|CD147—另一个新冠病毒入侵的关键靶点
网页2020年3月30日 · CD147，也称为Basigin或EMMPRIN，是一种高度糖基化的单次跨膜蛋白，相对分子质量为50kDa-60kDa，属于免疫球蛋白超家族。. 根据CD147来源不同，对其命名也有所不同，在人体内被称为basigin、白细胞活化相关M6抗原、肝癌细胞抗原Hab18G；在小鼠中被称为basigin或gp42；在大 ...
The Biological Function and Clinical Utilization of CD147 in …
网页2014年9月29日 · CD147 or EMMPRIN is a member of the immunoglobulin superfamily in humans. It is widely expressed in human tumors and plays a central role in the progression of many cancers by stimulating the secretion of matrix metalloproteinases (MMPs) and cytokines. CD147 regulates cell proliferation, apoptosis, and tumor cell migration, …
Circ Res 空军军医大学陈志南/边惠洁团队揭示CD147促进动脉粥样 …
网页2024年1月10日 · 动脉粥样硬化 CD147. 该研究揭示了CD147在斑块动态进展过程中发挥的作用及调控机制，并证实抗人CD147抗体可有效缓解动脉粥样硬化进展。. 缺血性心脏病和脑卒中是造成人类死亡的最主要原因，而动脉粥样硬化 (atherosclerosis)是导致其发生的病理基础。. 动脉粥样 ...
新冠病毒感染的第二个关键蛋白——CD147 - 知乎
网页2020年11月9日 · CD147，又名Basigin或EMMPRIN，是一种跨膜糖蛋白，属于免疫球蛋白超家族。 CD147在多种肿瘤细胞和组织中高表达，通过诱导基质金属蛋白酶的分泌促进肿瘤浸润及转移。
CD147: an integral and potential molecule to abrogate hallmarks …
网页2023年11月7日 · CD147 is a molecule critically involved in the acquisition and propagation of hallmarks of cancer and cancer-enabling characteristics. It is therefore one of the key driver molecules in cancer development, microenvironment adaptation, progression, metastasis, and resistance to therapies witnessed in many human cancers.
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