Busulfan - Wikipedia
网页Busulfan (Myleran, GlaxoSmithKline, Busulfex IV, Otsuka America Pharmaceutical, Inc.) is a chemotherapy drug in use since 1959. It is a cell cycle non-specific alkylating antineoplastic agent, in the class of alkyl sulfonates. Its chemical designation is 1,4-butanediol dimethanesulfonate.
Busulfan: MedlinePlus Drug Information
网页Busulfan is used treat a certain type of chronic myelogenous leukemia (CML; a type of cancer of the white blood cells). Busulfan is in a class of medications called alkylating agents. It works by slowing or stopping the growth of cancer cells in your body. How should this medicine be used? Busulfan comes as a tablet to take by mouth once a day.
Busulfan (Myleran) Tablets: Uses & Side Effects - Cleveland Clinic
网页Busulfan is a chemotherapy medication that treats chronic myelogenous leukemia. This is a bone marrow cancer. It begins in your blood-forming cells and can spread to other areas of your body. This medication comes as a tablet that you can take by mouth with a glass of water as directed.
Busulfan - NCI - National Cancer Institute
网页2014年2月21日 · This page contains brief information about busulfan and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Busulfan Tablet - Uses, Side Effects, and More - WebMD
网页Busulfan is used to treat chronic myelogenous leukemia (CML). It does not cure the disease but helps to control it so that your quality of life is improved. Take this medication by mouth with or...
Busulfan oral/injection Uses, Side Effects & Warnings - Drugs.com
网页2024年4月25日 · Busulfan oral (taken by mouth) is used to treat the symptoms of chronic myelogenous leukemia (a type of blood cancer). Busulfan is not a cure for leukemia. Busulfan injection is used together with a medicine called cyclophosphamide, to prepare your body to receive a stem cell transplant from a donor's bone marrow.
Busulfan - StatPearls - NCBI Bookshelf - National Center for ...
网页2024年3月10日 · Busulfan is an alkylating antineoplastic agent administered to patients since the 1950s. The FDA-approved indication for busulfan is for use with cyclophosphamide as part of the regimen before allogeneic hematopoietic progenitor cell transplantation, specifically for patients with chronic myelogenous leukemia.
Busulfan: Dosage, Mechanism/Onset of Action, Half-Life
网页2020年2月17日 · Busulfan is an alkylating agent which reacts with the N-7 position of guanosine and interferes with DNA replication and transcription of RNA. Busulfan has a more marked effect on myeloid cells than on lymphoid cells and is also very toxic to hematopoietic stem cells. Busulfan exhibits little immunosuppressive activity.
Busulfan: Uses, Interactions, Mechanism of Action - DrugBank …
网页Busulfan is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells.
Busulfan (intravenous route) - Mayo Clinic
网页Busulfan injection is used in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for treatment of chronic myelogenous leukemia.