Acetone - Wikipedia
Current method. Acetone is produced directly or indirectly from propene. Approximately 83% of acetone is produced via the cumene process; [24] as a result, acetone production is tied to phenol production. In the cumene process, benzene is alkylated with propylene to produce cumene, which is oxidized by air to produce phenol and acetone:
New Insights into Acetone Metabolism - PMC - National Center …
2006年12月1日 · Overview of acetone metabolism. The boxed region depicts the novel pathway of propane metabolism uncovered in Gordonia sp. strain TY-5 (10, 11). Additional reactions that generate or degrade acetone are illustrated outside of the box.
On the mammalian acetone metabolism: from chemistry to …
2003年5月2日 · This paper reviews the chemistry of acetone in brief, the studies of acetone metabolism mostly in mammals, both in vivo and in vitro, and the toxicity of acetone. Attention is also paid to the possible physiological roles of acetone metabolism in humans and to the roles of acetone in disease processes. 2.
On the mammalian acetone metabolism: from chemistry to …
2003年5月2日 · Despite the description of the ways of acetone metabolism, its real role (s) is (are) still unknown in metabolic network. In this article, a trial is made to ascertain a comprehensive overview of acetone research extending discussion from chemistry to clinical implications.
Biochemistry, Ketone Metabolism - StatPearls - NCBI Bookshelf
2023年4月24日 · Ketone metabolism consists of the oxidation and utilization of ketone bodies by mitochondria, especially in organs with high energy demand. This process produces NADH and FADH2 for the electron transport chain and delivers acetyl CoA for gluconeogenesis.
Molecular Mechanisms for Ketone Body Metabolism, Signaling …
2022年11月21日 · The ketone bodies (KBs) β-hydroxybutyrate and acetoacetate are important alternative energy sources for glucose during nutrient deprivation. KBs synthesized by hepatic ketogenesis are catabolized to acetyl-CoA through ketolysis in extrahepatic tissues, followed by the tricarboxylic acid cycle and electron transport chain for ATP production.
[Acetone metabolism: biochemistry, toxicology and clinical
1997年5月11日 · In the article, the routes of acetone metabolism are summarized and the conditions in which acetonemia occurs, are taken into account. Acetonemiae are classified as to be of exogenous and endogenous origin, and the biochemical mechanisms of the development of different acetonemiae are analyzed.
Possible physiological roles of acetone metabolism in humans
1999年9月1日 · Here, an integrative model for the role of acetone metabolism is presented that orders the events occurring in acetonemia in sequence: (i) acetone participates in pH regulation; and (ii) acetone degradation in the liver both contributes to glucostatic function of the liver and provides C 3 fragments to peripheral tissues as additional fuel. The ...
Structural Basis for the Mechanism of ATP-Dependent Acetone ...
2017年8月3日 · Schuhle, K. & Heider, J. Acetone and butanone metabolism of the denitrifying bacterium “Aromatoleum aromaticum” demonstrates novel biochemical properties of an ATP-dependent aliphatic ketone ...
Ketones and the Heart: Metabolic Principles and Therapeutic ...
2023年3月30日 · The ketone bodies beta-hydroxybutyrate and acetoacetate are hepatically produced metabolites catabolized in extrahepatic organs. Ketone bodies are a critical cardiac fuel and have diverse roles in the regulation of cellular processes such as metabolism, inflammation, and cellular crosstalk in multiple organs that mediate disease.