Pharmacokinetic/Pharmacodynamic Modeling of Spiramycin …
2021年9月25日 · Spiramycin is usually prescribed in veterinary medicine as a therapy for respiratory diseases in birds and ruminants, mastitis, arthritis, and foot-rot in cattle, and infectious gastroenteritis in pigs [7]. In addition, it shows prominent …
Macrolide Use in Animals - MSD Veterinary Manual
Tilmicosin is labeled for SC administration in cattle and sheep and PO in swine and cattle. Tiamulin is labeled for administration PO in swine, and tildipirosin is labeled for SC use in cattle. Clarithromycin and azithromycin are not labeled for veterinary use in the US, but are frequently prescribed for extralabel oral use.
Spiramycin - Food and Agriculture Organization
The Forty-seventh Session of the Committee recommended the following MRLs for spiramycin in cattle, chickens and pigs. For cattle and chickens MRLs are expressed as the sum of spiramycin and neospiramycin, for pigs as spiramycin equivalents (antimicrobially active residues).
Macrolides and lincosamides in cattle and pigs: Use and …
2014年5月1日 · The first macrolide intended for food animal use was spiramycin, which was introduced in the early 1960s, followed by erythromycin and tylosin in the early 1970s (Prescott, 2008). The most recent macrolide to be approved in the EU was tildipirosin in 2011.
Pharmacokinetics and tissue residues of spiramycin in cattle after ...
Pharmacokinetic variables of spiramycin and its distribution in muscle, liver, kidney, and injection sites were studied in 18 mixed-sex 1-year-old calves to assess drug withdrawal time after 2 IM administrations of 100,000 IU of spiramycin/kg of body weight at 48-hour intervals.
cattle with I.E.B.P. demonstrated the excellent efficacy of spiramycin at an optimal dose of 100,000 IU/kg. The rec ommended frequency of administration in curative treat ment is 2 injections at a 48 hour interval and the clinical recovery rate is 80- …
Spiramycin - fao.org
Spiramycin is a macrolide antibiotic that is produced by certain strains of Streptomyces ambofaciens and used in oral or parenteral formulations for the treatment or prophylaxis of local or systemic diseases in cattle and pigs. It had been previously evaluated at the thirty-eighth and forty-third meetings of the Committee.
Effect of spiramycin and tulathromycin on abomasal emptying …
We conclude that the labeled antimicrobial dose of spiramycin and tulathromycin increases the abomasal emptying rate in healthy milk-fed calves. Additional studies investigating whether spiramycin and tulathromycin exert a prokinetic effect in adult cattle with abomasal hypomotility appear indicated.
Spiramycin - University of Hertfordshire
2024年1月12日 · Used for the treatment of various infections, including gingivitis, stomatitis, glossitis, periodontitis and dental fistular). It has also been used for mastitis, arthritis, foot rot and also as a growth promotor. Examples of species treated. Poultry; Sheep; Cattle; Pigs; Cats; Dogs. Approval status.
Effect of spiramycin and tulathromycin on abomasal emptying …
In contrast, we demonstrated a statistically significant studies investigating whether spiramycin and tulathromycin exert a effect of spiramycin (25 mg/kg BW, IM) on abomasal emptying rate prokinetic effect in adult cattle with abomasal hypomotility appear in calves.