The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.
Here, the authors show that human PKD1 contains guanine quadruplex structures that cause mutagenic double stranded breaks. Efficiency of Hi-C methods is restrained by usage of enzymes irrelevant ...
RNA modifications are changes to the chemical composition of ribonucleic ... An example of RNA modification is the addition of a methylated guanine nucleotide cap to the 5 -end of messenger ...
A crystal structure of the compound bound to NSP14 shows that TDI-015051 occupies the enzyme’s guanine cap-binding pocket, adjacent to S-adenosylhomocysteine, which is a molecule involved in the ...
Chemical Engineering is concerned with the design and operation of processes which convert materials and energy into the higher value products we use every day. It understands the processes which ...
Nano-heterostructures and hetero-junctions, in particular, are gaining tremendous traction in chemical sensing. Because of unusual surface properties, materials with nano-scale features are ...
Kirillov was the commander of Russia’s Radiation, Chemical and Biological Protection Forces, and is thought to be the most senior military figure assassinated in Russia since the country invaded ...
Key Laboratory of Colloid and Interface Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China ...
P.O. Box B, Frederick 21702, Maryland, United States Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook11794, New York, United States Department of Applied ...
We show that while Cas9 enforces strict guanine selection through the rigidity of its interacting arginine dyad ... we introduced the xCas9 mutations in the X-ray structure of SpCas9 (PDB 4UN3) and ...
Over $1,000,000 in scholarship funds are awarded to 300+ students annually. The ACS Scholars Program awards renewable scholarships to undergraduate students from historically underrepresented groups ...