tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Despite being an RNA polymerase II transcript, the 3’ end of MALAT1 is produced not by canonical cleavage/polyadenylation but instead by recognition and cleavage of the tRNA-like structure by RNase P ...

To elucidate the structural basis of tRNA recognition and discrimination by the 'discriminating' GluRS, we determined the crystal structure of the GluRS·tRNA Glu complex.

The findings reveal how the absence of TRMT10A leads to a reduction in specific transfer RNA (tRNA) levels, disrupting protein synthesis in the brain and impairing synaptic structure and function.

Genome Res 19: 347-359. View Publication Wilusz, J.E., Freier, S.M., and Spector, D.L. (2008) 3’ end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. Cell 135: ...

A pioneering study undertaken by a Kumamoto University research team shed light on the crucial role of TRMT10A, a tRNA methylation enzyme, in sustaining brain function. The findings show how TRMT10A ...

Unlike inoculation, vaccination seeks to use a heterotypical pathogen (like cowpox), inactivated or weakened pathogens, or specific elements (units) of a pathogen which can induce immunity against ...

In the small intestine there are also specialised structures called villi which have a tiny hair-like structure poking into the small intestine to absorb digested food. If we stretched out all the ...

Most of them have not panned out. in production games from studios like Guerilla and Naughty Dog have been in development for some time. The purchase of Bungie signified a tilt by Sony towards ...

Structure is the order the different sections of a song or piece of music are played in. BOY 2: Hey, I’ve got some new lyrics. “Our tempos steady like a well times yo-yo.” GIRL 3 ...

Back in 2011, Swedish explorers Peter Lindberg and Denis Asberg were combing the Baltic Sea for treasure when their sonar ...