【导读】结直肠癌(CRC)是全球癌症相关死亡率的第二大原因，而p53作为一种被广泛认可的肿瘤抑制因子，促进了CRC的发展。USP36属于去泛素化酶家族，参与多种癌症的进展。然而，在结直肠癌中USP36调控p53信号通路的潜在分子机制尚不清楚。9月29 ...

While a study suggests that spike proteins found in the COVID-19 vaccine can affect a tumor suppressor gene, it is not proof ...

Hereditary breast cancers are caused by germline mutations, which are genetic mutations inherited at conception and so called ...

Colorectal cancer (CRC) stands as the second most common cause of cancer-related mortality globally and p53, a widely recognized tumor suppressor, contributes to the development of CRC.

我国是全球癌症最高发的国家之一，其中肺癌是“头号杀手”。根据组织病理学特点不同，肺癌可分为非小细胞肺癌和小细胞肺癌。肺腺癌是非小细胞肺癌最常见的组织学亚型，是全球癌症相关死亡的主要原因，是一个巨大的公共卫生负担。尽管靶向和免疫治疗取得了一定进展，但肺 ...

Known commonly as p53, it is a tumor suppressor gene with the power to block potentially cancerous cells from becoming malignant. But when mutated, p53 loses its cancer-fighting ability, dramatically ...

A potential new treatment for an aggressive form of prostate cancer has shown promise in lab tests. American scientists have ...

When researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate ...

Researchers at the University of Michigan Rogel Cancer Center have recently uncovered a novel subtype of aggressive prostate ...

Discover the potential of chronotherapy, a groundbreaking approach to cancer treatment that aligns chemotherapy with your ...

Data show that p300 KAT inhibitor KB-9558 was highly selective against human papillomavirus (HPV) oncoproteins E6 and E7, and therefore drove ...

The advent of large-scale sequencing in both development and disease has identified large numbers of candidate genes that may be linked to important phenotypes. Validating the function of these ...