Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that ...

Further, the research team observed a notable diversity in macrophage types between the two tumor types. The pro-inflammatory M1 macrophages and inflammation-related markers were found to be ...

An international team of UK and US scientists discovered that the activity of macrophages -- a type of white blood cell that engulf pathogens and cancer cells -- can be used to predict whether or not ...

This will involve moving its first cancer drug into clinical trials, and starting work on projects involving macrophages and the role they play in inflammatory diseases. Bregenholt told ...

Macrophages have ability to easily penetrate ... Initial applications for therapeutic candidates will be in the treatment of solid tumors. Other potential applications include the disruption ...

Discover how immune iFRET biomarkers offer new insights into predicting response to neoadjuvant melanoma therapy, driving ...

Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in diverse ...