因此,通过药物抑制这一代偿途径,可以加剧肿瘤细胞因MYC驱动的RNA分解而经历的代谢压力,最终导致肿瘤细胞的死亡。 论文于近日发表在Cancer ...
高危神经母细胞瘤是一种起源于发育中的交感神经系统的儿童癌症,具有很强的化疗耐药性及隐匿性。尽管患者从放射学检查(如 X 射线、CT、MRI ...
2020年5月4日,中山大学附属孙逸仙纪念医院&广东省人民医院在Molecular Cancer (中科院一区 IF=27.7)期刊上在线发表题为 "circNFIB1 inhibits lymphangiogenesis and lymphatic ...
【导读】SETD8是一种在几种癌症中过度表达的甲基转移酶,它使H4K20和其他非组蛋白靶点(如PCNA或p53)单甲基化。9月28日,西班牙国立癌症研究中心研究人员在期刊《Cell Death&Disease》上发表了研究论文,题为“SETD8 ...
Researchers have identified a critical variation in medulloblastomas, a form of brain cancer in children. Their discovery of ...
Researchers have identified a critical group of medulloblastoma, a form of brain cancer in children, which is near incurable ...
Vital research findings pointing to improved treatment for children with Group 3 medulloblastoma brain tumors have been ...
Vital research findings pointing to improved treatment for children with brain tumours have been revealed in two major ...
本研究发现circ467可以通过结合eIF4A3提高c-Myc的蛋白翻译效率,从而促进CRC的恶性进展,该工作为CRC的进展机制和CRC治疗的潜在治疗靶点提供了新的 ...
Researchers at MUSC Hollings Cancer Center say that in the course of developing a new model for ovarian cancer, they’ve ...
Northwestern Medicine scientists have discovered a new mechanism that controls a specialized group of T-cells, known as ...