tail at the 3′ end of the mRNA. In addition, we do not yet understand the precise signalling pathways that coordinate histone synthesis in the cytoplasm and DNA replication in the nucleus ...

Nucleosomes lacking H2B and H3 tails exhibit weakened interactions between histone tails and nucleosomal DNA, leading to less stable nucleosome structure.

The basic organizational unit of the genome is a nucleosome, which is a short segment of DNA wound around a complex of eight histone subunits. Each of these histones has a tail region which can be ...