Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that is mediated predominantly by noncompetitive inhibition of HIV-1 reverse transcriptase. Swallow whole; do not break tabs ...

Spanish researchers found that high plasma efavirenz levels correlated with CNS symptoms even after weeks or months of treatment. However, in a substudy of an ACTG trial, late neuropsychiatric ...

Efavirenz/emtricitabine/tenofovir disoproxil fumarate are medications used to treat HIV. They are antiretroviral drugs combined in one pill, taken once a day. Two of the drugs (emtricitabine and ...

Patients stopping efavirenz-based combination therapy might be well advised to continue their NRTIs for 24 to 48 hours after discontinuing efavirenz to avoid prolonged NNRTI monotherapy.

Efavirenz is an important drug for treating HIV infection, but it has negative effects that can significantly impact patients' quality of life over time. It causes neuropsychiatric disorders and ...

Some medications need to be taken with food to be most effective. Efavirenz should be taken on an empty stomach. Many anti-HIV medications can be taken with or without food. However, some of them need ...