The San Francisco 49ers will wear alternate uniforms that include white pants as they prepare for what promises to be the hottest NFL game played at Levi’s Stadium. Temperatures are expected to ...

Head coach Kyle Shanahan said Monday that the 49ers are hopeful Kittle (hamstring) returns to practice this week, Eric Branch of the San Francisco Chronicle reports. Kittle was a mid-week addition ...

The San Francisco 49ers (3-3) currently have 15 players on the injury report, including Jordan Mason, ahead of their Sunday, Oct. 20 matchup with the Kansas City Chiefs (5-0) at Levi's Stadium ...

This will sting a bit. Wide receiver Jauan Jennings will not be available when the San Francisco 49ers face the Kansas City Chiefs. He is dealing with a hip injury he sustained in the 49ers' Week ...

The San Francisco 49ers have already dealt with their fair share of issues this season. The defending NFC champions have seen multiple key players miss time due to injury, with even more ...

SANTA CLARA -- Even after all the success the San Francisco 49ers had the past few seasons, a two-game skid and a string of injuries early in the season can raise some doubts for any team.

For most of Shanahan’s tenure in the Bay, the San Francisco 49ers have owned his buddy Sean McVay’s club. SoFi Stadium on Sunday was, again, a sea of red. The hosts were winless and coming off ...

The 49ers are trying to stave off the dreaded Super Bowl hangover and have gotten off to a 1-2 start, and now video has emerged of head coach Kyle Shanahan confronting star wideout Brandon Aiyuk ...

A bizarre situation unfolded at the 49ers’ final practice of the week ahead of Sunday’s game against the Patriots. Wide receiver Brandon Aiyuk had a confrontation with head coach Kyle Shanahan ...

Deebo Samuel was projected miss multiple weeks with a calf injury that forced him out of the San Francisco 49ers game in Week 3 against the Los Angeles Rams. But now, it’s looking like a ...